Reference

Common Migraine Triggers

Identifying your personal triggers is one of the most powerful steps in managing migraine. Triggers vary widely between individuals, and what affects one person may not affect another.

Important: triggers are not causes

Migraine is a neurological condition — triggers don't cause migraine, they activate it in someone who is already predisposed. The same is true for many other conditions (asthma, epilepsy, autoimmune disease). This is why triggers vary so much between people: the underlying biology differs.

Hormonal

Menstrual cycle

Estrogen drop in the late luteal phase (just before and during menstruation) is a major trigger. Up to 70% of women with migraine report menstrual-related attacks.

Ovulation

Mid-cycle estrogen surge can also trigger attacks in some patients.

Hormonal medications

Combined oral contraceptives, hormone replacement therapy, and some IUDs can change migraine patterns — sometimes making them worse, sometimes better.

Pregnancy and menopause

Migraine often improves during pregnancy (especially 2nd and 3rd trimesters) and after menopause, though patterns vary.

Lifestyle and environmental

Sleep changes

Both too little and too much sleep can trigger attacks. Shift work, jet lag, and irregular sleep schedules are common culprits.

Skipped meals

Fasting or low blood sugar is a frequent trigger. Eating regular meals helps stabilize migraine threshold.

Dehydration

Even mild dehydration (1-2% body weight) can trigger attacks in susceptible people.

Weather changes

Barometric pressure drops, high humidity, sudden temperature shifts, and bright sunlight are commonly reported.

Strong sensory input

Bright or flickering lights, loud sounds, strong smells (perfume, cleaning products, smoke).

Dietary

Alcohol

Red wine is the most commonly cited trigger, though any alcohol can trigger attacks — usually within a few hours.

Aged cheeses

Tyramine content (also in cured meats, fermented foods, some soy products) is a possible trigger.

Caffeine

Both excess and withdrawal can trigger migraine. Daily intake should be kept consistent.

MSG and nitrates

Found in some processed foods, Chinese food, deli meats. Evidence is mixed but patient reports are common.

Artificial sweeteners

Aspartame in particular has been reported as a trigger, though evidence is limited.

Stress and emotional

Acute stress

Work deadlines, arguments, major life events.

Let-down stress

Many patients report migraine attacks on weekends, vacations, or after a stressful project ends — the "let-down" effect.

Anxiety and depression

Both are more common in people with migraine and can lower the threshold for attacks.

Emotional exhaustion

Burnout, sleep deprivation, and prolonged stress all contribute.

Physical

Intense exercise

Vigorous activity can trigger attacks, especially in hot weather or at altitude.

Sexual activity

Some patients report migraine with sexual activity — usually benign but should be discussed with a doctor.

Neck strain

Poor posture, especially with prolonged screen time.

Head trauma

Concussion and even minor head injuries can trigger or worsen migraine patterns.

Medications and substances

Medication overuse

Using acute migraine medications (triptans, NSAIDs, acetaminophen) more than 10-15 days per month can cause medication-overuse headache (MOH), which makes migraine patterns worse.

Vasodilators

Some blood pressure medications (especially nitrates) and certain supplements can trigger attacks.

Hormonal contraception

Combined oral contraceptives can worsen migraine with aura — important to discuss with a provider.

How to find your personal triggers

The most reliable method is a migraine diary. Track each attack along with:

  • Date and time the attack started
  • Severity and duration
  • What you ate in the past 24 hours
  • Sleep duration the night before
  • Stress level (1-10) and major events
  • For women: where you are in your menstrual cycle
  • Weather changes, travel, or schedule shifts
  • Any medications taken (and dose)

After 3-6 months, patterns usually emerge. Apps like Migraine Buddy, Bearable, and BonTriage can simplify tracking and surface patterns automatically.

Don't over-restrict

Trying to avoid every possible trigger can backfire — anxiety, restriction, and loss of normalcy can themselves lower the migraine threshold. Focus on the 2-3 triggers that are most clearly linked to your attacks, not on eliminating everything.

If controlling your triggers isn't enough

When lifestyle changes and standard preventive medications don't bring attacks under control, procedures like TEMMA target the underlying migraine pathway directly — without daily medication.

Learn About TEMMA