There is no single “best” treatment for migraine — what works depends on your specific type, frequency, severity, medical history, and personal preferences.
Most patients benefit from a combination approach — preventive medication plus acute medication plus lifestyle modifications. When that combination is not enough, procedures like TEMMA may be appropriate.
Taken at the onset of a migraine attack to stop or reduce its severity. Used no more than 2 days per week to avoid medication-overuse headache.
Sumatriptan, rizatriptan, and others. Target serotonin receptors and reduce dural inflammation.
Ibuprofen, naproxen, diclofenac. Anti-inflammatory pain relief.
An older medication that constricts blood vessels and reduces migraine pain.
Newer class (ubrogepant, rimegepant) that block CGRP. Used when triptans are not appropriate.
Taken daily (or monthly, for some injectables) to reduce migraine frequency and severity over time.
Erenumab, fremanezumab, galcanezumab, eptinezumab. Monthly or quarterly injections. Modern, well-tolerated.
Propranolol, metoprolol. Originally developed for blood pressure, but effective for migraine prevention.
Amitriptyline, venlafaxine. Used at low doses for migraine prevention.
Topiramate, valproate. Effective for some patients but with more side effects.
FDA-approved for chronic migraine. Injections every 12 weeks.
Non-drug options that use electrical or magnetic stimulation to interrupt migraine activity.
External trigeminal nerve stimulator. Worn on the forehead for 20 minutes daily.
Single-pulse transcranial magnetic stimulation. Held to the back of the head.
Wearable remote electrical neuromodulation device. Controlled by smartphone.
Often underused but important components of a comprehensive migraine plan.
Common triggers include sleep changes, certain foods, stress, hormonal changes, weather shifts, and sensory stimuli.
Consistent sleep–wake times are one of the most powerful migraine modulators.
Moderate aerobic exercise has been shown to reduce migraine frequency in many patients.
Cognitive behavioral therapy, biofeedback, and mindfulness have strong evidence in migraine.
Identifying food triggers (often under-emphasized). Hydration, regular meals, and limiting alcohol are common starting points.
For patients who have not found adequate relief with other options, several procedures are available.
A new application of MMA embolization for severe migraine. Same-day procedure, drug-free, intended to be long-lasting.
FDA-approved for chronic migraine. Injections every 12 weeks across 31 head and neck sites.
Local anesthetic injections near specific nerves. Used for both treatment and prevention.
An implanted device that stimulates a facial nerve cluster involved in migraine. Used in highly refractory cases.
A consultation with a migraine specialist is the fastest way to find the right combination for you.
Schedule Your Visit